Multiblock copolypeptides of elastin-based polypeptides and mussel foot proteins with stimuli-responsiveness and surface-adhesive, methods of preparing thereof and use thereof
US12049491B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2018 |
| Grant date | Jul 30, 2024 |
| Priority date | — |
| Expiry date | Dec 28, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/735
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to a multiblock copolypeptide having stimulus responsivity and surface adhesiveness. The multiblock copolypeptide of the present disclosure, which is composed of an elastin-based polypeptide and a mussel foot protein, can form self-assembled core-shell structures and hydrogels exhibiting reversible change in response to temperature stimulation and can be used usefully for biomedical applications due to remarkably superior surface adhesiveness.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.