Patent · US Active

Engineered CD46-specific effector cells and uses thereof in the treatment of cancer

US12049511B2 · kind B2 · utility

0Cited by
161References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 2017
Grant dateJul 30, 2024
Priority date
Expiry dateMar 30, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2510/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Engineered effector cells, such as chimeric antigen receptors (CARs), are used for enhanced immunogenic response to specific antigen, such as CD46. Disclosed herein are compositions and methods of treatment a cancer overexpressing CD46, which comprises a pharmaceutical composition comprising an engineered effector cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.