Two-tailed self-delivering siRNA
US12049627B2 · kind B2 · utility
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77References
28Claims
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Key dates
| Filing date | Oct 15, 2020 |
| Grant date | Jul 30, 2024 |
| Priority date | — |
| Expiry date | Jun 2, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are compositions and methods comprising two-tailed siRNAs (tt-siRNAs) that exhibit unprecedented cellular uptake and silencing. Also provided are methods of treating neurological and other diseases with the two-tailed siRNAs of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.