Cystatin C and Cystatin 9 to treat gut inflammation caused by thermal injury
US12053511B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jun 16, 2020 |
| Grant date | Aug 6, 2024 |
| Priority date | — |
| Expiry date | Feb 24, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/8139
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes a composition and method of modulating a dysregulated gut-derived inflammation following a thermal injury comprising: identifying a mammal in need of treatment for the dysregulated gut-derived inflammation following the thermal injury; and providing the mammal with a recombinant Cystatin 9 (CST9) and Cystatin C (CSTC) in a synergistic amount sufficient to restrain or prevent a life-threatening, unrestrained systemic dysregulated gut-derived inflammation in the mammal caused by the thermal injury.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.