Patent · US Active

Sulfonylurea derivatives and uses thereof

US12054461B2 · kind B2 · utility

0Cited by
24References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 11, 2020
Grant dateAug 6, 2024
Priority date
Expiry dateSep 13, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.