Substituted heterocycles as aldehyde dehydrogenase inhibitors
US12054475B2 · kind B2 · utility
0Cited by
3References
30Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 17, 2023 |
| Grant date | Aug 6, 2024 |
| Priority date | — |
| Expiry date | Oct 17, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided herein are novel heterocyclic compounds, for example, compounds of Formula (IV-C). Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases, retinoid pathway activation, and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH) or as a male contraceptive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.