Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction
US12054478B2 · kind B2 · utility
0Cited by
4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 14, 2022 |
| Grant date | Aug 6, 2024 |
| Priority date | — |
| Expiry date | Sep 14, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to the field of medicinal chemistry, in particular to a phenyl triazole MLL1-WDR5 protein-protein interaction inhibitor (I) and a preparation method thereof, and pharmacodynamics experiments prove that the compound of the present disclosure has relatively strong MLL1-WDR5 protein-protein interaction inhibition activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.