Patent · US Active

Universal self-regulating mammalian cell line platform for the production of biologics

US12054733B2 · kind B2 · utility

0Cited by
5References
12Claims
0Family size

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Inventors

Key dates

Filing dateJun 15, 2018
Grant dateAug 6, 2024
Priority date
Expiry dateJan 26, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2800/80
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are genetic control circuits, cells, and methods that use a repressor polypeptide to reduce the transcription rate of an exogenous therapeutic polypeptide encoding gene in response to a change in condition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.