Methods of protein production using anti-senescence compounds
US12054762B2 · kind B2 · utility
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15References
30Claims
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Key dates
| Filing date | Apr 22, 2008 |
| Grant date | Aug 6, 2024 |
| Priority date | — |
| Expiry date | Dec 25, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.