Transcriptome sequencing through random ligation
US12054773B2 · kind B2 · utility
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26Claims
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Key dates
| Filing date | Aug 26, 2020 |
| Grant date | Aug 6, 2024 |
| Priority date | — |
| Expiry date | Aug 26, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6844
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides methods and systems for producing full-length sequencing information of transcriptomes from single cells or from the bulk. Random ligation and circularization of barcoded or non-barcoded complementary deoxyribonucleic molecules can be used to provide a circular template for amplification and subsequent sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.