Patent · US Active

Wafer level sequencing flow cell fabrication

US12057309B2 · kind B2 · utility

0Cited by
21References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 9, 2022
Grant dateAug 6, 2024
Priority date
Expiry dateJun 9, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2021/058
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for forming sequencing flow cells can include providing a semiconductor wafer covered with a dielectric layer and forming a patterned layer on the dielectric layer. The patterned layer has a differential surface that includes alternating first surface regions and second surface regions. The method can also include attaching a cover wafer to the semiconductor wafer to form a composite wafer structure including a plurality of flow cells. The composite wafer structure can then be singulated to form a plurality of dies. Each die forms a sequencing flow cell. The sequencing flow cell can include a flow channel between a portion of the patterned layer and a portion of the cover wafer, an inlet, and an outlet. Further, the method can include functionalizing the sequencing flow cell to create differential surfaces.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.