Membrane for blood purification

US12059658B2 · kind B2 · utility

Assignee

• GAMBRO LUNDIA AB · SE

Inventors

• Adriana BOSCHETTI-DE-FIERRO · Hechingen, DE
• Manuel Voigt · Hechingen, DE
• Bernd Krause · Liederbach, DE
• Markus Hornung · Nehren, DE
• Markus Storr · Echterdingen, DE
• Heinrich Behr · Hechingen, DE
• Werner Beck · Rottenburg am Neckar, DE
• Carina Zweigart · Schömberg, DE
• Reinhold Buck · Bad Buchau, DE
• Philipp Herbst · Mössingen, DE
• Joachim Loercher · Mössingen, DE
• Arnd Wochner · Dotternhausen, DE

Key dates

• Filing date: May 4, 2023
• Grant date: Aug 13, 2024
• Expiry date: May 4, 2043

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01D2325/20
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.