Patent · US Active

Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo[4,5-d]pyrimidines and their use in treating conditions associated with elevated levels of CX3CR1 and/or CX3CL1

US12060380B2 · kind B2 · utility

0Cited by

1References

47Claims

0Family size

Assignee

Kancera AB · SE

Inventors

Jan Vågberg · Sollentuna, SE
Styrbjörn Byström · Solna, SE
Elisabeth Olsson · Sollentuna, SE
Mattias Jonsson · Uppsala, SE

Key dates

Filing date	Jul 5, 2019
Grant date	Aug 13, 2024
Priority date	—
Expiry date	Jul 21, 2041

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There is provided a compound of formula (I), wherein R1, R2, Q1 and formula (X) are as defined herein, which compounds are useful in the treatment of diseases and disorders associated with elevated levels of CX3CR1 and/or CX3CL1, in particular acute and/or chronic inflammation, eye diseases, lung diseases, skin diseases, joint and/or bone diseases, autoimmune diseases, cardiovascular diseases, metabolic diseases, brain diseases, neurodegenerative diseases, pain, cancer, liver diseases, kidney diseases, gastrointestinal diseases, human immunodeficiency virus and mood disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.