Patent · US Active

Ligand discovery and gene delivery via retroviral surface display

US12061187B2 · kind B2 · utility

1Cited by

2References

20Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Michael Birnbaum · Arlington, US
Connor Dobson · Somerville, US

Key dates

Filing date	Mar 23, 2020
Grant date	Aug 13, 2024
Priority date	—
Expiry date	Jun 15, 2043

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/5047
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.