PD-1 variant immunomodulatory proteins and uses thereof
US12065476B2 · kind B2 · utility
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Key dates
| Filing date | Jun 14, 2019 |
| Grant date | Aug 20, 2024 |
| Priority date | — |
| Expiry date | Feb 23, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/03
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are immunomodulatory proteins comprising variant PD-1 polypeptides, nucleic acids encoding such proteins and engineered cells expressing such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.