Short/small hairpin RNA molecules

US12065647B2 · kind B2 · utility

Assignees

• DOW AGROSCIENCES LLC · US
• Queensland University of Technology · AU

Inventors

• Elane Fishilevich · Indianapolis, US
• Kenneth E. Narva · San Diego, US
• Xiaozeng Yang · Indianapolis, US
• Meghan Frey · Greenwood, US
• Murugesan Rangasamy · Zionsville, US
• Wendy Lo · Saint Paul, US
• Premchand Gandra · Zionsville, US
• Peter Michael Waterhouse · Canberra, AU

Key dates

• Filing date: Feb 22, 2019
• Grant date: Aug 20, 2024
• Expiry date: Feb 22, 2039

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A40/146
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This disclosure concerns compositions and methods for novel RNA inhibition molecules (e.g., small/short hairpin RNA (shRNA) molecules), polynucleotides encoding such molecules, use of such novel RNA inhibition molecules to inhibit a target gene by suppressing the expression of the mRNA of the target gene, and for application such as the of control insect pests, and transgenic plants that produce, and are protected, by these novel RNA inhibition molecules are described.