Patent · US Active

Vector and method for treating bietti's crystalline dystrophy

US12065663B2 · kind B2 · utility

0Cited by

0References

9Claims

0Family size

Assignee

CHIGENOVO CO., LTD · CN

Inventors

Liping Yang · 流花街道, CN
Shaohong Chen · Tianjin, CN
Ruixuan Jia · Beijing, CN
Fan Zhang · Lake Barrington, US
Saichao He · Beijing, CN
Tianyong Shi · Beijing, CN
Dandan Hao · Beijing, CN
Hongjie Pei · Beijing, CN
Luying Zeng · Beijing, CN

Key dates

Filing date	Jul 13, 2022
Grant date	Aug 20, 2024
Priority date	—
Expiry date	Jul 29, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14143
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application relates to a vector comprising a polynucleotide encoding CYP4V2 and a promoter operably linked to the polynucleotide encoding CYP4V2. The vector described herein has a good expression effect, high expression speed, and more stable expression intensity. The present application also provides cells, pharmaceutical compositions, and kits comprising the vector, and methods for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.