Immune repertoire monitoring
US12065705B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Mar 22, 2019 |
| Grant date | Aug 20, 2024 |
| Priority date | — |
| Expiry date | Sep 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B30/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, methods provide for determining convergence of T cell receptor and/or B cell receptor repertoires in samples prior to a treatment and predicting a subjects response to the treatment based on the measured convergence frequency. In another aspect, methods provide for an immune receptor haplotype group and predicting a subjects potential or predisposition to be protected from or vulnerable to an adverse event following a treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.