Patent · US Active

Bispecific antigen binding construct

US12071486B2 · kind B2 · utility

0Cited by

10References

4Claims

0Family size

Assignee

argenx BV · BE

Inventors

Sebastian Van Der Woning · Deinze, BE
Christophe Blanchetot · Laarne, BE

Key dates

Filing date	Dec 21, 2018
Grant date	Aug 27, 2024
Priority date	—
Expiry date	Oct 10, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to bispecific and other multispecific antigen binding constructs. In certain aspects, the invention relates to bispecific antigen binding constructs comprising a single domain antibody (VHH) antigen binding region fused to an IgG Fc domain; a heavy chain-Fc domain portion of a conventional IgG antibody, and a light chain portion of a conventional IgG antibody. The bispecific antigen binding constructs of the invention are capable of targeting two different antigens separately or in a protein complex.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.