Viral vector constructs for delivery of nucleic acids encoding cytokines and uses thereof for treating cancer
US12071633B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Oct 13, 2021 |
| Grant date | Aug 27, 2024 |
| Priority date | — |
| Expiry date | Jan 6, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides the gene therapy compositions comprising vectors (e.g., viral vectors) suitable for delivery of nucleic acids encoding immunomodulatory proteins or functional fragments thereof, and methods of using the same. Certain aspects of the disclosure are directed to an adeno-viral vector (AAV) delivery of nucleic acids encoding two or more immunomodulatory proteins or functional fragments thereof to a tumor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.