Proteins comprising kallikrein related peptidase 2 antigen binding domains and their uses

US12077585B2 · kind B2 · utility

Assignee

• JANSSEN BIOTECH, INC. · US

Inventors

• Rajkumar Ganesan · Blue Bell, US
• John Lee · Philadelphia, US
• Jinquan Luo · Malvern, US
• Theresa McDevitt · Warminster, US
• Fei Shen · Philadelphia, US
• Degang Song · Wynnebrook Manor, US
• Raymond Brittingham · Spring House, US
• Sathyadevi VENKATARAMANI · Blue Bell, US
• Sanjaya Singh · Sandy Hook, US
• Yonghong Zhao · Eagleville, US
• Fang Yi · Collegeville, US
• Sherry Lynn La Porte · Horsham, US

Key dates

• Filing date: Jul 23, 2020
• Grant date: Sep 3, 2024
• Expiry date: Oct 19, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.