Anti-thymidine kinase antibodies

US12077600B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Hartmut Duefel · Schlehdorf, DE
• Alfred Engel · Tutzing, DE
• Frank Kroner · Schwaigwall, DE
• Thomas Meier · Cherbourg, FR
• Sandra Rutz · Penzberg, DE
• Michael Schraeml · Penzberg, DE
• Gloria Tabares · Penzberg, DE
• Ulrike Kurtkaya · Penzberg, DE
• Boris Pinchuk · Penzberg, DE
• Christina Zimmermann · Penzberg, DE

Key dates

• Filing date: Oct 13, 2020
• Grant date: Sep 3, 2024
• Expiry date: Jul 6, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to a novel monoclonal antibody that specifically binds to a conformation dependent epitope on human thymidine kinase 1 (hTK-1; SEQ ID NO:1), to methods for quantifying hTK-1 employing the antibody and to the use of the anti-hTK-1 antibody in quantifying hTK-1.