Variable lymphocyte receptors that target the brain extracellular matrix and methods of use
US12077609B2 · kind B2 · utility
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30Claims
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Key dates
| Filing date | Dec 19, 2019 |
| Grant date | Sep 3, 2024 |
| Priority date | — |
| Expiry date | Aug 22, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.