Bifidobacterium longum subsp. infantis with fimbriae and applications thereof
US12077749B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 31, 2023 |
| Grant date | Sep 3, 2024 |
| Priority date | — |
| Expiry date | Aug 31, 2043 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A strain of Bifidobacterium longum subsp. infantis Y46 with fimbriae (BI_Y46) includes a unique flagella structure, exhibits strong abilities in utilizing 2′-fucosyllactose (2′-FL), galacto-oligosaccharides and short-chain galacto-oligosaccharides, possesses excellent probiotic characteristics with higher levels of extracellular polysaccharides and surface proteins than a strain of Bifidobacterium longum subsp. infantis M63 (BI_M63) and a strain of Bifidobacterium longum subsp. infantis ATCC 15697 (BI_15697), and further displays stronger ability to tolerate gastric acid and inhibitory ability of the cell-free supernatant to Escherichia coli ATCC 15922 than the BI_15697. Therefore, the BI_Y46 has excellent probiotic potential and can be used to develop probiotics, infant food, prebiotic products, and functional foods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.