Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
US12083111B2 · kind B2 · utility
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29Claims
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Key dates
| Filing date | Aug 17, 2021 |
| Grant date | Sep 10, 2024 |
| Priority date | — |
| Expiry date | Apr 29, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.