Polypeptides binding to human complement C5
US12083160B2 · kind B2 · utility
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4References
15Claims
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Key dates
| Filing date | Sep 20, 2021 |
| Grant date | Sep 10, 2024 |
| Priority date | — |
| Expiry date | Sep 20, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6 X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86% identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.