Lipid particles for nucleic acid delivery
US12083224B2 · kind B2 · utility
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11References
17Claims
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Key dates
| Filing date | Apr 1, 2019 |
| Grant date | Sep 10, 2024 |
| Priority date | — |
| Expiry date | Nov 16, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleic acid immunization is achieved by delivering a nucleic acid (NA), e.g., a mRNA or a DNA, encapsulated within a lipid-NA nanoparticle. The NA encodes an immunogenic compound of interest. The lipid-NA nanoparticle is effective for in vivo delivery of NA to a vertebrate cell, including upon administration to a subject. The lipid-NA nanoparticle are incorporated in pharmaceutical compositions for immunizing subjects against various diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.