Liquid ventilator and method to induce tidal liquid ventilation and/or hyporthermia

US12083271B2 · kind B2 · utility

Assignees

• SOCPRA SCIENCES ET GENIE S.E.C. · CA
• ECOLE NATIONALE VETERINAIRE D'ALFORT · FR
• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• Université Paris—Est Créteil Val de Marne · FR

Inventors

• Philippe Micheau · Sherbrooke, CA
• Renaud Tissier · Paris, FR
• Matthias Kohlhauer · Saint-Maurice, FR
• Julien Mousseau · Candiac, CA
• Mathieu Nadeau · Compton, CA
• Jonathan Vandamme · North Vancouver, CA

Key dates

• Filing date: Apr 12, 2019
• Grant date: Sep 10, 2024
• Expiry date: May 23, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2230/46
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.