Patent · US Active

Microfluidic analysis of ligand induced cell expression

US12083512B2 · kind B2 · utility

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26Claims

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Assignee

European Molecular Biology Laboratory · DE

Inventors

Hongxing Hu · Shanghai, CN
Samantha Seah · Heidelberg, DE
Christoph Merten · Heidelberg, DE

Key dates

Filing date	Jan 13, 2017
Grant date	Sep 10, 2024
Priority date	—
Expiry date	Jan 13, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC40B20/08
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to the field of microfluidics and in particular to analysing the gene expression of a cell in response to a ligand expressed in the same microfluidic compartment. By barcoding the transcriptome of the cell and of the expression system generating the ligand, the effect of the ligand on the cell expression can be discerned. The invention provides microfluidic compartments and methods for this purpose.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.