Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses

US12084417B2 · kind B2 · utility

Assignee

• Cybin UK Ltd · GB

Inventors

• Peter Rands · London, GB
• George Knight · London, GB
• Richard Chubb · London, GB
• Derek John Londesbrough · Sunderland, GB
• Tiffanie Benway · London, GB
• Zelah Joel · London, GB

Key dates

• Filing date: Mar 31, 2023
• Grant date: Sep 10, 2024
• Expiry date: Mar 31, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/05
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Syntheses of compounds of Formula III from compounds of Formula I via compounds of Formula II are described, as well as particular compounds of Formula III, or pharmaceutically acceptable salts thereof, compositions comprising such compounds, and uses thereof. For example, certain of these compounds and compositions of Formula III have uses in the treatment of psychiatric or neurological disorders.