Proteins comprising CD3 antigen binding domains and uses thereof

US12084501B2 · kind B2 · utility

Assignee

• JANSSEN BIOTECH, INC. · US

Inventors

• Adam Zwolak · Bala-Cynwyd, US
• Raymond Brittingham · Spring House, US
• Scott Ronald Brodeur · New Hope, US
• Rajkumar Ganesan · Blue Bell, US
• Sherry Lynn La Porte · Horsham, US
• Jinquan Luo · Malvern, US
• Fang Yi · Collegeville, US
• Colleen Kane · Radnor, US
• Triveni K. Bhatt · Perkasie, US

Key dates

• Filing date: Mar 23, 2022
• Grant date: Sep 10, 2024
• Expiry date: Mar 30, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.