Patent · US Active

Recombinant bacterium with a high PHA yield and the construction method thereof

US12084648B2 · kind B2 · utility

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Key dates

Filing dateMar 9, 2023
Grant dateSep 10, 2024
Priority date
Expiry dateMar 9, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/01
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A recombinant bacterium with a high PHA yield and its construction method provide an engineered microorganism that can be used for the production of polyhydroxyalkanoate (PHA). A recombinant Ralstonia eutropha with a high PHA yield includes a promoter for upregulating a phaJ gene and further includes a mutant phaC gene. The recombinant Ralstonia eutropha can be used for producing 3-hydroxybutyrate-co-3-hydroxyhexanoate (PHBHHx) in PHA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.