Patent · US Active

Packaging oligonucleotides into virus-like particles

US12084655B2 · kind B2 · utility

0Cited by

80References

10Claims

0Family size

Assignee

CHECKMATE PHARMACEUTICALS, INC. · US

Inventors

Evan David WALTERS · Watertown, US
Frank Hennecke · Göttingen, DE

Key dates

Filing date	Apr 8, 2019
Grant date	Sep 10, 2024
Priority date	—
Expiry date	Sep 23, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2795/18142
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to processes for producing compositions comprising (i) a virus-like particle of an RNA bacteriophage, and (ii) aggregated oligonucleotides, wherein said aggregated oligonucleotides are packaged into said virus-like particle. The invention further provides processes for producing nucleotide compositions comprising aggregated oligonucleotides suitable for use in the aforementioned processes before. Moreover, the invention further provides nucleotide compositions comprising aggregated oligonucleotides. Furthermore, the invention further provides compositions comprising (i) a virus-like particle of an RNA bacteriophage, and (ii) aggregated oligonucleotides, wherein said aggregated oligonucleotides are packaged into said virus-like particle.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.