Patent · US Active

Recombinant hARSA that crosses the blood brain barrier

US12084690B2 · kind B2 · utility

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0References

18Claims

0Family size

Assignee

LINNO PHARMACEUTICALS INC. · CN

Inventors

Zhaozhong Han · Franklin, US
Hongya PAN · Shanghai, CN
Haiyang Li · Shanghai, CN
Lingyu Li · Chongqing, CN

Key dates

Filing date	Oct 17, 2023
Grant date	Sep 10, 2024
Priority date	—
Expiry date	Oct 17, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application pertains to a fusion protein, comprising a transferrin-binding protein, and an arylsulfatase A (ARSA) or functionally active fragment thereof, wherein the transferrin-binding protein comprises a peptide, an antibody or an antigen-binding fragment of the antibody capable of binding transferrin. The other aspect of the present application provides the preparing methods and the uses of the fusion protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.