Composite tubular material prepared from extracellular matrix and synthetic polymer, and preparation method thereof
US12090254B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2023 |
| Grant date | Sep 17, 2024 |
| Priority date | — |
| Expiry date | Feb 28, 2043 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29D23/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present disclosure discloses a composite tubular material and a preparation method thereof. The tubular material is prepared from extracellular matrix and directionally arranged synthetic polymer fibers through compounding; the synthetic polymer fibers serve as an internal skeleton, a fiber diameter ranges from 1 μm to 2000 μm, a fiber angle ranges from 0° to 180°, and a wall thickness ranges from 1 μm to 1000 μm; and extracellular matrix components are obtained from human or animal tissue through decellularization. According to the present disclosure, the tubular material with bioactivity and excellent mechanical properties can be prepared from the synthetic polymer and the natural material extracellular matrix through compounding; the synthetic polymer fibers with controllable fiber angle and diameter serve as the internal skeleton of the tubular material, and accordingly the tubular material has the mechanical properties of resistance to bending and squeezing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.