Implantable living electrodes and methods for use thereof

US12090323B2 · kind B2 · utility

Assignees

• The Trustees of the University of Pennsylvania · US
• Thomas Jefferson University · US

Inventors

• Daniel Kacy Cullen · Madison, US
• James P. Harris · Philadelphia, US
• John A. Wolf · Philadelphia, US
• Han-Chiao Isaac Chen · Penn Valley, US
• Douglas H. Smith · Boothwyn, US
• Mijail Serruya · Providence, US

Key dates

• Filing date: Jun 25, 2021
• Grant date: Sep 17, 2024
• Expiry date: Feb 18, 2042

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/0531
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

In one aspect, the invention comprises an implantable living electrode comprising a substantially cylindrical extracellular matrix core; one or more neurons implanted along or within the substantially cylindrical extracellular matrix core, the one or more neurons including one or more optogenetic or magnetogenetic neurons proximal to a first end of the implantable living electrode.