Reagents and methods for bioorthogonal labeling of biomolecules in living cells
US12091391B2 · kind B2 · utility
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Key dates
| Filing date | May 2, 2016 |
| Grant date | Sep 17, 2024 |
| Priority date | — |
| Expiry date | Aug 29, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2521/501
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Tetrazine non-canonical amino acids, methods for genetic encoding proteins and polypeptides using the tetrazine amino acids, proteins and polypeptides comprising the tetrazine amino acids, and compositions comprising the proteins and polypeptides having at least one post-translational modification thereof comprising in vivo reaction with the incorporated tetrazine amino acid and a second molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.