RNA structure library
US12091775B2 · kind B2 · utility
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Key dates
| Filing date | Jun 27, 2017 |
| Grant date | Sep 17, 2024 |
| Priority date | — |
| Expiry date | Dec 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B20/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An RNA probe containing RNA functional structural units is prepared by the following steps: (1) recognizing one or more stem structures contained in the RNA based on RNA sequence information; (2) extracting a motif region with reference to the one or more recognized stem structures; (3) adding an assistive stem region to the extracted motif region; and (4) adding a barcode region, which represents a complementary sequence to a DNA barcode sequence, to the assistive stem region. Also provided is a method for detecting a protein-binding RNA by using an RNA probe containing RNA functional structural units.
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