Systems and methods for biomolecule quantitation
US12092642B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Jan 19, 2022 |
| Grant date | Sep 17, 2024 |
| Priority date | — |
| Expiry date | Jan 19, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Systems and methods for obtaining qualitative or quantitative measurements of proteoforms of polypeptides are described. The described methods include measurements of affinity reagent binding on single-molecule polypeptide arrays to distinguish between polypeptide isoforms. The described methods may provide high resolution quantitative comparisons of proteoforms with very low copy numbers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.