Patent · US Active

Pharmaceutical composition containing alkynyl compound and preparation method and application thereof

US12097195B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignees

ASCENTAGE PHARMA (SUZHOU) CO., LTD. · CN
ASCENTAGE PHARMA GROUP CORP LIMITED · CN
GUANGZHOU HEALTHQUEST PHARMA CO., LTD. · CN

Inventors

Yanqiong LIN · Suzhou, CN
Jianfeng Wen · Suzhou, CN
Feng Xu · Durham, US
Jiaan HUANG · Suzhou, CN
Shixiong LI · Suzhou, CN
Xiaoling He · Longbeilingcun, CN
Shihe LIANG · Suzhou, CN

Key dates

Filing date	Dec 9, 2019
Grant date	Sep 24, 2024
Priority date	—
Expiry date	Mar 25, 2040

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a pharmaceutical composition containing alkynyl compound, a preparation method thereof and its application. The present invention discloses a pharmaceutical composition comprising an active pharmaceutical ingredient and an available pharmaceutical excipient; The active pharmaceutical ingredient is 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-benzamide, or its pharmaceutical acceptable salt; The available pharmaceutical excipients includes diluents and lubricants. The pharmaceutical composition can effectively improve the bioavailability of the alkynyl compound, has good dissolution and stability, and improve the drug safety.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.