Brain-targeting single domain antibodies and purification methods
US12098200B1 · kind B1 · utility
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19Claims
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Key dates
| Filing date | Oct 12, 2022 |
| Grant date | Sep 24, 2024 |
| Priority date | — |
| Expiry date | Oct 12, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/569
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are single domain antibodies (sdAbs) configured for passing the blood brain barrier in a human or mammal brain. Methods of using such sdAbs are also described herein, such as methods of binding to brain cells, binding with and transporting other sdAbs with beneficial functionalities, binding to and transporting biochemical or pharmaceutical species with beneficial functionalities, and treating, diagnosing, or prophylactically treating a disease, malignancy, or condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.