Manufacturing a biologic pharmaceutical using causal models
US12099046B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 3, 2019 |
| Grant date | Sep 24, 2024 |
| Priority date | — |
| Expiry date | Sep 1, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for optimizing a process of manufacturing a biologic pharmaceutical. In one aspect, the method comprises repeatedly performing the following: i) selecting a configuration of input settings for manufacturing a batch of a biologic pharmaceutical based on a causal model that measures current causal relationships between input settings and a measure of a quality of batches of the biological pharmaceutical; ii) determining a measure of the quality of a batch of the biological pharmaceutical manufactured using the configuration of input settings; and iii) adjusting, based on the measure of the quality of the batch of the biological pharmaceutical, the causal model.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.