Reagents, methods, and systems for detecting therapeutic agents to monitor adherence to nucleoside reverse transcriptase inhibitor metabolites
US12099056B2 · kind B2 · utility
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1References
15Claims
0Family size
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Key dates
| Filing date | Dec 17, 2021 |
| Grant date | Sep 24, 2024 |
| Priority date | — |
| Expiry date | Apr 7, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2430/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides novel compounds, reagents, systems, and methods for detecting a metabolite related to a NRTI in a biological sample, and uses thereof in monitoring adherence to pre-exposure prophylaxis. Such reagents comprise NRTI derivatives, analogs, NRTI derivatives conjugates, along with antibodies directed to same, which are useful for antibody-based methods, such as a lateral flow immunoassay and other point of care devices.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.