System, method and computer-accessible medium for detecting structural disorder(s) using magnetic resonance imaging

US12100121B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Jia Guo · Hangzhou City, CN
• Scott A. Small · Millerton, US

Key dates

• Filing date: Jun 15, 2021
• Grant date: Sep 24, 2024
• Expiry date: Jun 15, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30016
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An exemplary system, method, and computer-accessible medium for detection of structural disorder(s) of patient(s) can be provided which can include, for example, receiving magnetic resonance imaging (MRI) information of the portion(s), generating gadolinium (“Gd”) enhanced map(s) based on the MRI information using a machine learning procedure(s), and detecting the structural disorder(s) of the patient(s) based on a GD contrast of the Gd enhanced map(s). The Gd enhanced map(s) can be a full dosage Gd enhanced map. The machine learning procedure can be a convolutional neural network. The MRI information can include (i) a low-dosage Gd MRI scan(s), or (ii) a Gd-free MRI scan(s). The Gd contrast can be generated in the Gd enhanced map(s) using a T2-weighted MRI image of the portion(s). Structural disorder(s) can include Stroke, tumor, trauma, infection, Multiple sclerosis and/or other inflammatory disease.