ACE inhibitory peptide composition derived from ginkgo protein and preparation method and application thereof

US12102661B2 · kind B2 · utility

Assignee

• Northeast Agricultural University · CN

Inventors

• Juncai HOU · Jingwei, CN
• Zhanmei JIANG · Jingwei, CN
• Jiage MA · Jingwei, CN
• Ruijie Shi · Yuncheng, CN
• Jialun HU · Jingwei, CN
• Meng LI · Surrey, CA
• Liya GU · Jingwei, CN

Key dates

• Filing date: Jan 20, 2023
• Grant date: Oct 1, 2024
• Expiry date: Jan 20, 2043

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides ACE inhibitory peptide composition derived from ginkgo protein and preparation method and application thereof, belonging to the technical field of food and medicine. The ACE inhibitory peptide composition derived from ginkgo protein mainly consists of six small molecular peptides with amino acid sequences of GFDGR (SEQ ID NO. 1), NDPGR (SEQ ID NO. 2), LDQTYRP (SEQ ID NO. 3), REHETIIL (SEQ ID NO. 4), LRMPGPPSDDY (SEQ ID NO. 5) and LRMPGPPSDDYER (SEQ ID NO. 6). The specific preparation process includes preparation of ginkgo protein, hydrolysis of ginkgo protein, enzymolysis and hydrolysis of ginkgo protein to obtain crude ACE inhibitory peptide, and separation and purification of ACE inhibitory peptide composition derived from ginkgo protein.