Patent · US Active

Pre-loadable biological heart valve capable of rapid rehydration and preparation method thereof

US12102733B2 · kind B2 · utility

0Cited by

4References

20Claims

0Family size

Assignees

VENUS MEDTECH (HANGZHOU), INC. · CN
Sichuan University · CN

Inventors

Yunbing Wang · Sunnyvale, US
Gaocan Li · Chengdu, CN
Yang Lei · Palo Alto, US
Li-Xi Yang · San Francisco, US
Hou-Sen Lim · Singapore, SG
Dajun Kuang · Zhejiang, CN
Jincheng Yu · Beijing, CN

Key dates

Filing date	May 6, 2021
Grant date	Oct 1, 2024
Priority date	—
Expiry date	Jun 14, 2043

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/40
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

A method for preparing a pre-loadable biological heart valve capable of rapid rehydration includes performing a cross-linking treatment, wherein a biological valve is cross-linked by soaking in an aqueous glutaraldehyde solution; performing a hydrophilic treatment, wherein the biological valve is soaked in a solution containing a hydrophilic molecule and a condensing agent, to allow the hydrophilic molecule to be immobilized on the biological valve by chemical grafting; and performing a drying treatment, wherein the biological valve after the hydrophilic treatment and the cross-linking treatment is dried to obtain the pre-loadable biological heart valve capable of rapid rehydration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.