TEAD inhibitors and methods of uses thereof

US12103915B2 · kind B2 · utility

Assignee

• INSILICO MEDICINE IP LIMITED

Inventors

• Xiao Ding · Chesterfield, US
• Jinxin Liu · Shanghai, CN
• Feng Ren · Shanghai, CN
• Jianfei Wan · Shanghai, CN
• Wei Zhu · Suzhou, CN

Key dates

• Filing date: Dec 5, 2023
• Grant date: Oct 1, 2024
• Expiry date: Dec 5, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The disclosure provides for compounds and methods for modulating or inhibiting TEAD. Further provided herein are pharmaceutical compositions comprising the TEAD inhibitors and methods of treatment using the TEAD inhibitors or the pharmaceutical compositions.