Pyclen-based macrocyclic ligands, chelates thereof and uses thereof
US12103927B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Mar 29, 2019 |
| Grant date | Oct 1, 2024 |
| Priority date | — |
| Expiry date | Mar 29, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/0482
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A ligand of Formula (A): wherein each R1 independently represents a chromophore group; L1, L2 and L3 each independently represents a single bond or a linker; and X1, X2 and X3 each independently represents a hydrogen atom, a coupling function or a bio-vectorizing group. Also, a process for manufacturing the ligand and to a process for manufacturing a chelate by complexation by the ligand of a rare-earth cation, preferably a lanthanide cation. Further, a use of the ligand and/or the chelate in biological imaging and/or photoluminescence imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.