Patent · US Active

Method for constructing library of cell-free DNAs in body fluids and application thereof

US12104203B2 · kind B2 · utility

0Cited by

0References

14Claims

0Family size

Assignee

BGI SHENZHEN · CN

Inventors

Mingyue Wang · Tangxia, CN
Longqi LIU · Lo Wu, CN
Chuanyu Liu · Longbeilingcun, CN
Liang Wu · Auburn, US
Jiangshan Xu · Lo Wu, CN
Yue Yuan · Longbeilingcun, CN
Zhouchun Shang · Longbeilingcun, CN

Key dates

Filing date	Nov 27, 2017
Grant date	Oct 1, 2024
Priority date	—
Expiry date	Dec 26, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2535/122
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for constructing a library of cell-free DNAs in body fluids, comprising directly acting a transposase or an endonuclease on a body fluid sample, fragmenting the cell-free DNAs within, and performing amplification to obtain a library. Also provided is a test kit using the present method for prenatal diagnosis or early detection of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.