Usages of recombinant extracellular vesicles
US12105091B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 6, 2018 |
| Grant date | Oct 1, 2024 |
| Priority date | — |
| Expiry date | Sep 8, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2496/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure relates to the field of research and clinical usage of extracellular vesicles. More in particular, this disclosure relates to usages of recombinant extracellular vesicles comprising a) a self-assembling protein that directs its own release through vesicles as a luminal membrane-bound protein and b) a heterologous marker. Indeed, the disclosure provides recombinant extracellular vesicles that can be used as a biological reference material in methods to quantify extracellular vesicles in a sample, and/or, that can be used to calibrate a device for sample extracellular vesicles analysis, and/or, that can be used to evaluate the isolation process of extracellular vesicles. This disclosure thus relates to improving the accuracy of an extracellular vesicle-based diagnosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.